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SCI Abstract
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Multicenter Validation of Cerebellar Motor Learning Biomarker for Spinocerebellar Degenerations
Objectively quantifying cerebellar motor dysfunction remains a challenge in clinical trials. The Adaptability Index, deriv...
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Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei
The cerebellar nuclei form the main output structures of the cerebellum and are composed of a deeply conserved set of cell...
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Cerebellar Cognitive Affective Syndrome in Spinocerebellar Ataxia Type 6
Background: Spinocerebellar ataxia type 6 (SCA6) has traditionally been classified as a "pure" cerebellar syndro...
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Multimodal PET Findings in -Related Primary familial Brain Calcification Caused by a Novel Homozygous Frameshift Mutation
Primary familial brain calcification (PFBC) is a rare inherited neurological disorder characterized by bilateral intracran...
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Chiari I Malformation as a Human Disease Model of Cerebellar Cognitive–Affective Dysfunction
Chiari malformation type I (CM1) is traditionally viewed as a structural disorder of the posterior fossa characterized by ...
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The CCAS-Scale in Chiari Malformation Type I: A Cerebellar-Focused Cognitive Assessment with Clinical Utility
Background/Objectives: The Cerebellar Cognitive-Affective Syndrome (CCAS) scale, introduced by Schmahmann, was prospective...
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The Real Life of Ataxia Patients Without a Vertical Family History: a Twenty-year Experience in South Brazil
Studies of hereditary ataxias (HA) without vertical family history are necessary for designing diagnostic protocols. We de...
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EEG-ECeG Coherence Mapping of Human Cerebro-cerebellar Projections: An Exploratory Study
The cerebellar and cerebral cortices are powerfully connected via reciprocal, crossed projections which mediate their coor...
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Preoperative Speech Impairments as Precursors of Posterior Fossa Syndrome in Children with Brain Tumours
Preoperative speech deficits in children with posterior fossa tumours (PFTs) may be linked to postoperative speech impairm...
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Low-Titer Anti-GAD Cerebellar Ataxia: Evidence That Diagnosis Should Extend Beyond Serum Antibody Levels – A Case Report and Systematic Review
Anti-glutamic acid decarboxylase (anti-GAD) antibodies are associated with cerebellar ataxia. Although high antibody titer...
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Purkinje Cell Loss and Changes in Basket Cell Morphology in Essential Tremor and Other Cerebellar Degenerative Diseases: A Postmortem Study of 332 Brains
Essential tremor (ET) is among the most prevalent neurological diseases. Postmortem studies have demonstrated Purkinje cel...
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Multimodal PET Imaging Unveils Early Metabolic Compensation Mechanisms and Dopaminergic Degeneration in Parkinson’s Disease
This study aimed to elucidate the interplay between cerebral glucose metabolism and dopaminergic degeneration in Parkinson...
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Post-Infectious Cerebellitis: A Systematic Review of Aetiology, Clinical Presentation, Treatment, and Outcomes
Post-infectious cerebellitis is an immune-mediated cerebellar inflammatory syndrome that follows a preceding infection (or...
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Blood Glucose Homeostasis is Preserved in Patients with Mild-to-moderate Spinocerebellar Ataxia Type 2
Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disorder that shows cerebellar glucose hypometabolism, systemi...
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Target Interpretability and Functional Mapping of rTMS and Theta-Burst Stimulation of the Cerebellar Vermis and Midline Cerebellum: A Scoping Review
The cerebellar vermis and midline cerebellum contribute to motor, oculomotor, vestibular, cognitive, affective, autonomic,...
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TNIP1 As A Potential Factor In Neuronal Survival, Growth and Differentiation in the Cerebellar Cortex
Tumor Necrosis Factor-Induced Protein 1 (TNIP1) is a well-known ubiquitin-binding signaling molecule involved in innate an...
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Motor Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke
Cerebellar ataxia results in debilitating impairments in balance, gait, and cognition, with no established effective treat...
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Age-Related Volumetric Changes of the Posterior Cranial Fossa and its Structures in Stroke Patients
The posterior cranial fossa (PCF) contains critical neural structures, including the cerebellum and brainstem, whose volum...
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Anatomy of Cerebro-cerebellar Circuits in Motor Control
Cerebral cortex and cerebellum are intimately connected enabling them to perform their functions in learning, controlling ...
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-Related Disorders: Description of New Variant and Phenotypic Spectrum Based on Age of Onset
The VPS13 family plays a crucial role in mitochondrial stabilization. Biallelic pathogenic variants in VPS13D are classica...
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Progression of Gait Ataxia in Spinocerebellar Ataxia Type 2: Clinical Utility of Digitally Measured Gait Metrics
Identifying digital biomarkers for gait ataxia remains a key research priority in spinocerebellar ataxias (SCAs), given th...
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The Cerebellar Neuropsychiatric Rating Scale Version 2: Development and Validation
The affective component of the cerebellar cognitive affective / Schmahmann syndrome (CCAS) reflects neuropsychiatric sympt...
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The Cerebellar Cognitive Affective Syndrome in Essential Tremor Plus
The latest tremor classification suggested to stratify patients with Essential Tremor (ET) into pure (pET) and plus (ET-pl...
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Anti-Tr/DNER Antibody-Associated Paraneoplastic Neurological Syndrome Complicated with Warthin Tumor: a Case Report and Literature Review
Generally, paraneoplastic neurological syndrome (PNS) associated with anti-delta/notch-like epidermal growth factor-relate...
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Evaluating Repetitive Transcranial Magnetic Stimulation in Spinocerebellar Ataxia: A Meta-Analysis of Efficacy and Safety
To evaluate the efficacy and safety of repetitive Transcranial Magnetic Stimulation (rTMS) in Spinocerebellar Ataxia (SCA)...
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Effect of Aminopyridines on Oculomotor Dysfunction in Anti-GAD Ataxia: A Brief Report
Aminopyridines (APs) enhance Purkinje cell excitability and are effective for several cerebellar and ocular motor syndrome...
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How the Human Brain’s Cerebro-cerebellar Loops of Social-cognitive Forword Control Were Copied to Create “Agency” in Artificial Intelligence (A.I.) Computing Systems, Including a Note to Mark Zuckerberg
Van Overwalle F, Manto M, Leggio M, Delgado-García J. The sequencing process generated by the cerebellum crucially contrib...
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Pontine Functional Connectivity Gradients
The cerebellum contributes to a wide range of motor and non-motor functions through its extensive connections with much of...
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Genetic Insights in Hindbrain Abnormalities Through Network Analysis Expose Key Biological Pathways in Hindbrain Development
The number of known developmental disorders affecting the hindbrain is rapidly increasing due to advances in neuroimaging ...
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Repeat Expansions in a Chilean Cohort with Adult-Onset Cerebellar Ataxia
The diagnosis of hereditary ataxias caused by repeat expansions continue to present unique methodological challenges, espe...
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