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Modeling the functional impact of CPEB3 and CPEB4 dysregulation in autism: A theoretical–computational framework
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Irisin regulates mitochondrial function to support synaptogenesis in the developing hippocampus
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4-MEC potentially triggers CAV1 via the BDNF-TrkB signaling pathway
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Interweaving microglial senescence and gut microbiome dynamics in Alzheimer's disease – Mechanisms and therapeutic frontiers
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The effects of GLP-1 receptor agonists on Alzheimer's pathophysiology: A systematic review
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AdipoRon alleviates cerebral ischemic injury through AMPK-dependent microglial autophagy and phenotypic modulation
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Liproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation
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Optimized laminin surfaces induce spontaneous myelination by neonate mice dorsal root ganglia
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Sex-specific roles of neuronal TNFR1 in synaptic remodeling and stroke recovery
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Severity-dependent proteomic alterations in the rat hippocampus following pilocarpine-induced status epilepticus
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Glial-neuronal interactions via chemokine signaling in cerebral ischemia: Mechanisms and therapeutic implications
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Occurrence of neuronal dysfunction in mice with virus- or toxic-induced lesions in the central nervous system
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Stress-induced neuroinflammation and synaptic dysregulation: Linking HPA axis to glutamate and NMDA receptors
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A potential role for NADPH oxidase (NOX1/2) in mutant huntingtin-induced anomalous neurite outgrowth
Neurite growth is regulated by NADPH Oxidase (NOX1 and 2) and in this study, we investigate whether neuritic abnormalities...
Apelin-13 can regulate adipose-derived mesenchymal stem cells to improve traumatic brain injury
Traumatic brain injury (TBI) is divided into primary injury and secondary injury based on its pathophysiological processes...
Rethinking Parkinson's: The role of proteostasis networks and autophagy in disease progression
The prevalence of age-dependent disorders is estimated to significantly increase by 2050, yet there are currently no effec...
A critical role for the fascin family of actin bundling proteins in axon development, brain wiring and function
The actin cytoskeleton powers a wide range of cellular activities ranging from cell migration to membrane trafficking (Dom...
DAPK1 induces motor neuron apoptosis in hSOD1G93A-linked amyotrophic lateral sclerosis via regulating the Xiap/JNK pathway
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease marked by the progressive degeneration and loss of upp...
Sex-specific neuroprotection: Does BDNF shield girls from autism?
Autism Spectrum Disorder (ASD) is a multifaceted neurodevelopmental disorder characterized by deficits in social communica...
Modulation of Nrf-2/HO-1/HIF-1α/TFAM pathways by Arbutin in rat model of cerebral ischemic stroke
Globally, ischemic stroke (IS) continues to rank among the leading causes of permanent disability. Globally, around 15 mil...