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Managing Refractory Hypertension: A Case Study Exploring the Influence of ACE and ACTN3 Gene Polymorphisms
Managing Refractory Hypertension: A Case Study Exploring the Influence of ACE and ACTN3 Gene Polymorphisms
A case of an elderly female patient who experienced several phases of hypertensive emergencies during supervised training ...
Clinical Outcomes of Osimertinib Combined with Platinum-Based Chemotherapy in EGFR-Mutant Non-Small Cell Lung Cancer: A Retrospective Study
Clinical Outcomes of Osimertinib Combined with Platinum-Based Chemotherapy in EGFR-Mutant Non-Small Cell Lung Cancer: A Retrospective Study
To assess the clinical outcomes of osimertinib combined with platinum-based chemotherapy in patients with EGFR-mutant NSCLC
Post-Translational Modifications of Histones and Non-Histones in Liver Disease and Traditional Chinese Medicine Treatment: A Narrative Review
Post-Translational Modifications of Histones and Non-Histones in Liver Disease and Traditional Chinese Medicine Treatment: A Narrative Review
Reviewing the role and pathway mechanisms mediated by post-translational modifications of histones and non-histones in liv...
Bioinformatic Identification and Preliminary Validation of TP53, TGFB1, and NFE2L2 as Potential Ferroptosis-Related Regulators in Pancreatic Adenocarcinoma
Bioinformatic Identification and Preliminary Validation of TP53, TGFB1, and NFE2L2 as Potential Ferroptosis-Related Regulators in Pancreatic Adenocarcinoma
Exploring mechanisms of ferroptosis in pancreatic adenocarcinoma as a new direction for therapeutic research.
NAT2 Acetylation Phenotypes in India: A Narrative Review of Personalized TB Therapy
NAT2 Acetylation Phenotypes in India: A Narrative Review of Personalized TB Therapy
A narrative review of current research, focusing on studies related to NAT2 polymorphisms, pharmacogenomics, and tuberculo...
Construction and Validation of Multi-Omics Predictive Models for Colorectal Cancer Using Machine-Learning Approaches
Construction and Validation of Multi-Omics Predictive Models for Colorectal Cancer Using Machine-Learning Approaches
To construct a nomogram model to predict the survival of CRC patients using the clinical and pathological characteristics ...
Massive Hepatocellular Carcinoma with Insufficient Future Liver Remnant Achieved Complete Response After Two-Stage Hepatectomy Combined with Hepatic Arterial Infusion Chemotherapy and Lenvatinib-sintilimab: A Case Report
Massive Hepatocellular Carcinoma with Insufficient Future Liver Remnant Achieved Complete Response After Two-Stage Hepatectomy Combined with Hepatic Arterial Infusion Chemotherapy and Lenvatinib-sintilimab: A Case Report
A case of a patient with massive HCC who underwent conversion therapy consists of portal vein ligation and systemic therap...
Population-Based Assessment of Phenoconversion Potential in Switzerland: A Claims Data Study of Key Drug-Metabolizing Enzymes and Transporters
Population-Based Assessment of Phenoconversion Potential in Switzerland: A Claims Data Study of Key Drug-Metabolizing Enzymes and Transporters
To assess the risk of phenoconversion by identifying potential drug-drug-gene interactions involving the transporters OATP...
Molecular Epidemiology of Thalassemia in University Town, Chongqing: Spectrum of Pathogenic Variants and Implications for Carrier Screening
Molecular Epidemiology of Thalassemia in University Town, Chongqing: Spectrum of Pathogenic Variants and Implications for Carrier Screening
This study was designed to analyze the molecular epidemiological characteristics of thalassemia-associated genes in the Un...
Comparative Analysis of SLCO1B1 Gene Polymorphisms in Dyslipidemic and Normolipidemic Patients with Type 2 Diabetes Mellitus Residing at High Altitude
Comparative Analysis of SLCO1B1 Gene Polymorphisms in Dyslipidemic and Normolipidemic Patients with Type 2 Diabetes Mellitus Residing at High Altitude
Examining the association between SLCO1B1 gene polymorphisms and blood lipid metabolism in Tibetan patients with type 2 di...
Anaplastic Lymphoma Kinase Positive Aggressive Adult Lung Primary Inflammatory Myofibroblastoma Tumor: A Case and Literature Review
Anaplastic Lymphoma Kinase Positive Aggressive Adult Lung Primary Inflammatory Myofibroblastoma Tumor: A Case and Literature Review
This case reports a 39-year-old woman with recurrent fever, cough, sputum, chest tightness, and shortness of breath for mo...
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation
Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation
This work found a link between FAM198B and quercetin, and the regulatory effect of FAM198B on the MAPK pathway of GC.
Associations Between FTO Polymorphisms and Neuroblastoma Risk in Chinese Children
Associations Between FTO Polymorphisms and Neuroblastoma Risk in Chinese Children
Revealing that individuals with retroperitoneal Neuroblastoma and those with stage III+IV NB are more prone to exhibit FTO...
Molecular Genetic Analysis of a DMD Frameshift Mutation in a Boy with Duchenne Muscular Dystrophy by MLPA and Sanger Sequencing
Molecular Genetic Analysis of a DMD Frameshift Mutation in a Boy with Duchenne Muscular Dystrophy by MLPA and Sanger Sequencing
The combination of MLPA and Sanger sequencing technologies can help make a definite genetic diagnosis for DMD patients. Re...
Advances in the Clinical Use of Clopidogrel: A Review of Individualized Treatment Strategies and Monitoring Optimization Based on Genetic Polymorphisms
Advances in the Clinical Use of Clopidogrel: A Review of Individualized Treatment Strategies and Monitoring Optimization Based on Genetic Polymorphisms
we elucidate clopidogrel's pharmacokinetic properties and pharmacodynamic mechanisms and evaluate its clinical efficacy an...
Construction of a Nomogram Model for Predicting Prognosis in Breast Cancer Patients Based on the Expression of THRSP and ACACA Proteins Tissues
Construction of a Nomogram Model for Predicting Prognosis in Breast Cancer Patients Based on the Expression of THRSP and ACACA Proteins Tissues
Analyzing the expression of THRSP, ACACA proteins in breast cancer tumor tissues and their relationship with clinicopathol...
Dual EGFR L858R and KRAS G12A Mutations in Lung Adenocarcinoma: A Rare Case Report and Literature Review
Dual EGFR L858R and KRAS G12A Mutations in Lung Adenocarcinoma: A Rare Case Report and Literature Review
We presented a case of a newly diagnosed NSCLC patient harboring concurrent EGFR L858R and KRAS G12A mutations.
The Prevalence of Potential Drug-Drug-Gene Interactions: A Descriptive Study Using Swiss Claims Data
The Prevalence of Potential Drug-Drug-Gene Interactions: A Descriptive Study Using Swiss Claims Data
Prevalence of interactions between PGx drugs metabolized by CYP2C9, CYP2C19, & CYP2D6 & drugs that act as inhibito...
Association Between ABCB1 Gene Polymorphism with Hyperglycemia and MACE in Patients Undergoing Clopidogrel Treatment After PCI
Association Between ABCB1 Gene Polymorphism with Hyperglycemia and MACE in Patients Undergoing Clopidogrel Treatment After PCI
Evaluating effect of ABCB1 C3435T gene polymorphism with hyperglycemia on the risk of major adverse cardiovascular events ...
Ulcerative Colitis: Advances in Pathogenesis, Biomarkers, and Therapeutic Strategies
Ulcerative Colitis: Advances in Pathogenesis, Biomarkers, and Therapeutic Strategies
We provide a thorough assessment of UC by synthesizing recent progress in understanding its pathogenesis, diagnostic bioma...
Whole Exome Sequencing Reveals Novel Genetic Variants Associated with Atrial Septal Defect in a Tibetan Patient Cohort
Whole Exome Sequencing Reveals Novel Genetic Variants Associated with Atrial Septal Defect in a Tibetan Patient Cohort
Identifying novel genetic variants related to atrial septal defect within the Tibetan population using whole exome sequenc...
Genetic Landscape of VIP Pharmacogenomic Variants in the Kinh Vietnamese Population
Genetic Landscape of VIP Pharmacogenomic Variants in the Kinh Vietnamese Population
we study the high impact variants among 100 pharmacogenes which are involved in drug metabolism, transportation, oxidation...
Berberine Repairs Intestinal Mucosal Barrier by Targeting HSP90AA1 and MAPK14
Berberine Repairs Intestinal Mucosal Barrier by Targeting HSP90AA1 and MAPK14
Network pharmacology, mendelian randomization, molecular docking, and molecular dynamics simulations identifying potential...
Case Report: Successful Surgical Resection of PVTT Vp4 Hepatocellular Carcinoma Following Hepatic Arterial Infusion Chemotherapy Combined with Cadonilimab Plus Donafenib
Case Report: Successful Surgical Resection of PVTT Vp4 Hepatocellular Carcinoma Following Hepatic Arterial Infusion Chemotherapy Combined with Cadonilimab Plus Donafenib
We present a case report of a 41-year-old male diagnosed with diffuse HCC in the right lobe of the liver and tumor thrombu...
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF
Identifying differentially expressed genes (DEGs) in neuroblastoma (NB) through comprehensive bioinformatics analysis and ...
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
The correlation between single nucleotide polymorphisms in selected genes (CACNA1, CACNA1D, ABCB1, ACE, ADBR2, & NOS1A...
Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine
Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine
This review aim to delineate nuanced facets, advantageous and challenging, of Africa's genetic multiplicity vis-à-v...
Immune Microenvironment Alterations and Identification of Key Diagnostic Biomarkers in Chronic Kidney Disease Using Integrated Bioinformatics and Machine Learning
Immune Microenvironment Alterations and Identification of Key Diagnostic Biomarkers in Chronic Kidney Disease Using Integrated Bioinformatics and Machine Learning
Investigating immune cell infiltration, differential gene expression, pathway enrichment in CKD to identify key diagnostic...
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis
To examine hsa_circ_0078767 as a mediator of doxorubicin (DOX) resistance in OS
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma
The expression & prognostic value of POP family in ccRCC were analyzed & the relationship between POP7 & immun...
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