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A narrative review of the placebo effect: historical roots, current applications, and emerging insights
A narrative review of the placebo effect: historical roots, current applications, and emerging insights
Placebo is a term to define physiologically inactive compounds used in treatment that causes physical and emotional change...
Facilitators and barriers to generic and biosimilar medications in the Middle East and North Africa: insights from physicians and pharmacists—a systematic review
Facilitators and barriers to generic and biosimilar medications in the Middle East and North Africa: insights from physicians and pharmacists—a systematic review
The adoption of generic and biosimilar medications is crucial for improving healthcare accessibility and cost savings in t...
Unveiling cardiovascular and respiratory toxicities with monoclonal antibodies in multiple myeloma: disproportionality analysis from the FDA Adverse Event Reporting System
Unveiling cardiovascular and respiratory toxicities with monoclonal antibodies in multiple myeloma: disproportionality analysis from the FDA Adverse Event Reporting System
Monoclonal antibodies (mAbs) have revolutionized the treatment of multiple myeloma (MM), demonstrating remarkable effectiv...
Influence of cigarette smoking on drugs’ metabolism and effects: a systematic review
Influence of cigarette smoking on drugs’ metabolism and effects: a systematic review
Cigarette smoke continues to be widely used around the world and it contains several substances that can affect the pharma...
Genome-wide association study of direct oral anticoagulants and their relation to bleeding
Genome-wide association study of direct oral anticoagulants and their relation to bleeding
Direct oral anticoagulants (DOACs) are used to prevent and treat thromboembolic events in adults. We aimed to investigate ...
Exploring the comprehensive factors influencing tacrolimus pharmacokinetics in early renal transplant recipients: A population pharmacokinetic analysis
Exploring the comprehensive factors influencing tacrolimus pharmacokinetics in early renal transplant recipients: A population pharmacokinetic analysis
To establish a population pharmacokinetic (PopPK) model of tacrolimus in the early stages after renal transplantation and ...
Psychotropic polypharmacy impairs walking independence in post-stroke patients
Psychotropic polypharmacy impairs walking independence in post-stroke patients
Psychotropic drugs are associated with adverse outcomes in older adults. However, evidence on the effect of psychotropic u...
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study
This study aims to evaluate the effect of dapagliflozin (DAPA) on malignant ventricular arrhythmias (MVA) after acute myoc...
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system
The renin-angiotensin-aldosterone system (RAAS) is a vital endocrine system that plays a crucial role in maintaining homeo...
Efficacy and safety of pembrolizumab in the treatment of advanced hepatocellular carcinoma: a systematic review and meta-analysis
Efficacy and safety of pembrolizumab in the treatment of advanced hepatocellular carcinoma: a systematic review and meta-analysis
The efficacy and safety of pembrolizumab in treating advanced hepatocellular carcinoma (HCC) are inconsistent across studi...
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker
In advanced cancer patients the CYP3A4-mediated clearance of drugs is dependent on the severity of inflammation. In a stud...
Efficacy of cyclophosphamide for skin fibrosis in systemic sclerosis: a systematic review and single-arm meta-analysis
Efficacy of cyclophosphamide for skin fibrosis in systemic sclerosis: a systematic review and single-arm meta-analysis
Systemic sclerosis (SSc) is a chronic connective tissue disorder characterized by skin thickening with vascular and viscer...
Correction to: Effectiveness of Macrolides as Add-On Therapy to Beta-Lactams in Community-Acquired Pneumonia: A Meta-Analysis of Randomized Controlled Trials
Correction to: Effectiveness of Macrolides as Add-On Therapy to Beta-Lactams in Community-Acquired Pneumonia: A Meta-Analysis of Randomized Controlled Trials
Correction to: European Journal of Clinical Pharmacology (2025) 81:83–91After the pub...
Drug-related falls: proportion and impact of hospitalizations in geriatric departments on the prescription of fall-risk increasing drugs (FRIDs)
Drug-related falls: proportion and impact of hospitalizations in geriatric departments on the prescription of fall-risk increasing drugs (FRIDs)
The incidence of drug-related admissions in France was 8.5% in 2018, with falls being the 5 th cause of DRA. The scr...
Analysis of a medication discrepancy management platform in reducing medication discrepancy and influencing factors among elderly patients with polypharmacy
Analysis of a medication discrepancy management platform in reducing medication discrepancy and influencing factors among elderly patients with polypharmacy
This study aimed to investigate the impact of a medication discrepancy management platform on reducing medication discrepa...
Challenges of pediatric pharmacotherapy: A narrative review of pharmacokinetics, pharmacodynamics, and pharmacogenetics
Challenges of pediatric pharmacotherapy: A narrative review of pharmacokinetics, pharmacodynamics, and pharmacogenetics
Personalized pharmacotherapy, including for the pediatric population, provides optimal treatment and has emerged as a majo...
Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases
Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases
Selective androgen receptor modulators (SARMs) have demonstrated agonist activity on the androgen receptor in various tiss...
Correction to: Empagliflozin and colchicine in patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction: a randomized, double-blinded, three-arm parallel-group, controlled trial
Correction to: Empagliflozin and colchicine in patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction: a randomized, double-blinded, three-arm parallel-group, controlled trial
Cite this articleKhiali, S., Taban-Sadeghi, M., Sarbakhsh, P. et al. Correction to: Empagliflozin and colchicine in patien...
Pharmacokinetics of oral spironolactone in infants up to 2 years of age
Pharmacokinetics of oral spironolactone in infants up to 2 years of age
Spironolactone is a potassium sparing diuretic used for decades. Until now, pharmacokinetic (PK) studies of spironolactone...
Serotonin syndrome: A pharmacovigilance comparative study of drugs affecting serotonin levels
Serotonin syndrome: A pharmacovigilance comparative study of drugs affecting serotonin levels
Serotonin syndrome is a rare and potentially fatal adverse drug reaction caused by serotonergic drugs and is due to an inc...
Effect of azilsartan on myocardial remodeling after acute myocardial infarction
Effect of azilsartan on myocardial remodeling after acute myocardial infarction
To investigate the effect of azilsartan on myocardial remodeling after acute myocardial infarction (AMI). A total of 200 A...
Antidepressant use and the risk of seizure: a meta-analysis of observational studies
Antidepressant use and the risk of seizure: a meta-analysis of observational studies
The association between antidepressant use and the risk of seizures remains controversial. Therefore, this meta-analysis e...
Direct oral anticoagulants and the risk of adverse clinical outcomes among patients with different body weight categories: a large hospital-based study
Direct oral anticoagulants and the risk of adverse clinical outcomes among patients with different body weight categories: a large hospital-based study
Through predictable pharmacokinetics—including a convenient fixed-dose regimen, direct oral anticoagulants (DOACs) a...
Untapped options to reduce waste from blister packaging for tablets and capsules
Untapped options to reduce waste from blister packaging for tablets and capsules
In Europe, most medicines are taken orally and primarily packaged as single solid oral dosage forms (SODF) in blister cham...
The reference range of lamotrigine in the treatment of epilepsy in children: a systematic review
The reference range of lamotrigine in the treatment of epilepsy in children: a systematic review
This study intends to assess the reference range of lamotrigine concentration for treating childhood epilepsy. PubMed, Ovi...
Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?
Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?
Therapeutic drug monitoring of tacrolimus using trough concentration (Cmin) is mandatory to ensure drug efficacy and safet...
Association of clozapine and norclozapine levels with patient and therapy characteristics—focus on interaction with valproic acid
Association of clozapine and norclozapine levels with patient and therapy characteristics—focus on interaction with valproic acid
The goal of the study was to examine clozapine (CLZ) and norclozapine (NCLZ) therapeutic drug monitoring (TDM) data and as...
Clinical pharmacokinetics and pharmacodynamics of ivosidenib in Chinese patients with relapsed or refractory IDH1-mutated acute myeloid leukemia
Clinical pharmacokinetics and pharmacodynamics of ivosidenib in Chinese patients with relapsed or refractory IDH1-mutated acute myeloid leukemia
This study aimed to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of ivosidenib in Chinese patients with rela...
The benefit of omeprazole exposure on all-cause mortality and length of ICU/hospital stay might vary with age in critically ill pediatric patients: A cohort study
The benefit of omeprazole exposure on all-cause mortality and length of ICU/hospital stay might vary with age in critically ill pediatric patients: A cohort study
To investigate the association between proton pump inhibitors (PPIs) administration during hospitalization and mortality a...
Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review
Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review
To develop a population pharmacokinetic (PPK) model for methotrexate (MTX) dosage for all ages, assess the association bet...
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