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Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system
Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system
Over the past decades, a substantial portion of the population worldwide has been infected with varicella zoster and most ...
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms
Rhinovirus (RV) infection is a major cause of common colds and asthma exacerbations, with no antiviral drug available. Cur...
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population
Cancer treatment has improved over the past decades, but many cancer patients still experience adverse drug reactions (ADR...
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review
Despite various therapeutic attempts, an approved treatment for Methanol-induced optic neuropathy (MION), a sight-threaten...
Advances in artificial intelligence-based technologies for increasing the quality of medical products
Advances in artificial intelligence-based technologies for increasing the quality of medical products
Artificial intelligence (AI) is a technology that combines machine learning (ML) and deep learning. It has numerous usages...
Cellular and molecular aspects of drug resistance in cancers
Cellular and molecular aspects of drug resistance in cancers
Cancer drug resistance is a multifaceted phenomenon. The present review article aims to comprehensively analyze the cellul...
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery
Amphotericin B (AMB) is a drug used to treat vulvovaginal candidiasis (VVC), which is a fungal infection affecting the vag...
Trends analysis and future study of the pharmaceutical industry field: a scoping review
Trends analysis and future study of the pharmaceutical industry field: a scoping review
The main aim of this study was to explore and understand the emerging developments, changes, and patterns shaping the futu...
Electroceuticals: Unlocking the promise of therapies
Electroceuticals: Unlocking the promise of therapies
Electroceuticals refers to the constantly growing disciplines of bioelectric and bioelectronic medication. These include a...
High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test
High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test
High-performance liquid chromatography (HPLC) has emerged as a highly sensitive and versatile analytical technique for qua...
and assessment of curcumin loaded bile salt stabilized nanovesicles for oral delivery
and assessment of curcumin loaded bile salt stabilized nanovesicles for oral delivery
Bile salts enriched nanovesicles (bilosomes) have been attention worthy in the past few years due to their distinctive eff...
Evaluation of the consumption pattern and efficacy of Linezolid in COVID-19 hospitalized patients in a hospital in Tehran-Iran
Evaluation of the consumption pattern and efficacy of Linezolid in COVID-19 hospitalized patients in a hospital in Tehran-Iran
The inappropriate use of antibiotics increases the costs of treatment, antibiotic resistance, increased disease length and...
Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review
Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review
Leukocytoclastic vasculitis (LCV) is a small-vessel inflammatory condition that can rarely occur as an adverse drug reacti...
Efficacy and safety of different dosages of rituximab for myasthenia gravis: a single-arm meta-analysis
Efficacy and safety of different dosages of rituximab for myasthenia gravis: a single-arm meta-analysis
Rituximab (RTX) is one of the treatment options for refractory myasthenia gravis (MG), yet the optimal dosing schedule rem...
The impact of Mill. on gastrointestinal disorders: a comprehensive analysis through clinical trials, systematic review, and meta-analysis
The impact of Mill. on gastrointestinal disorders: a comprehensive analysis through clinical trials, systematic review, and meta-analysis
Rosa damascena Mill. has been studied in clinical trials for the treatment of diverse gastrointestinal diseases. The aim o...
Stearyl amine tailored spanlastics embedded within tetronic nanogel for boosting the repurposed anticancer potential of mebendazole: formulation, in vitro profiling, cytotoxicity assessment, and in vivo permeation analysis
Stearyl amine tailored spanlastics embedded within tetronic nanogel for boosting the repurposed anticancer potential of mebendazole: formulation, in vitro profiling, cytotoxicity assessment, and in vivo permeation analysis
Mebendazole (MBZ) is an anthelmintic drug that was repurposed as an anti-cancer agent. This study aimed at formulating MBZ...
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review
Alzheimer’s disease (AD) is a neurological disease that causes memory loss over time. Current therapies are limited ...
Multi-functionalization of reduced graphene oxide nanosheets for tumor theragnosis: Synthesis, characterization, enzyme assay, in-silico study, radiolabeling and in vivo targeting evaluation
Multi-functionalization of reduced graphene oxide nanosheets for tumor theragnosis: Synthesis, characterization, enzyme assay, in-silico study, radiolabeling and in vivo targeting evaluation
In this study, a combination of nanotechnology, organic synthesis and radiochemistry were utilized in order to design an e...
Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review
Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review
Fruit vinegar is one of the most famous fruit byproducts worldwide with several unique properties. There are two types of ...
Electrochemical evaluation of nivolumab used in cancer treatment with differential pulse voltammetry: A novel approach with single-use pencil graphite electrode
Electrochemical evaluation of nivolumab used in cancer treatment with differential pulse voltammetry: A novel approach with single-use pencil graphite electrode
Nivolumab is used in a treatment called immunotherapy, which helps the immune system cells to attack cancer cells. The ele...
Ropivacaine suppresses the progression of renal cell carcinoma through regulating the lncRNA RMRP/EZH2/CCDC65 axis
Ropivacaine suppresses the progression of renal cell carcinoma through regulating the lncRNA RMRP/EZH2/CCDC65 axis
Renal cell carcinoma (RCC) is a common malignancy. Local anesthetics were displayed powerful effects against various cance...
Atypical extrapyramidal manifestation of a typical antipsychotic with serotonergic antidepressant
Atypical extrapyramidal manifestation of a typical antipsychotic with serotonergic antidepressant
Typical antipsychotics are known to produce extrapyramidal side effects such as drug induced parkinsonism, acute dystonia,...
Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury
Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury
Dexamethasone-induced neurotoxicity has been previously reported. However, the molecular mechanisms are still not complete...
Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran
Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran
As classical health technology assessment models fail to predict the complexities of related impacts, the application of m...
Immediate hypersensitivity reaction to levetiracetam: a case report study
Immediate hypersensitivity reaction to levetiracetam: a case report study
Anticonvulsant drugs are one of the most common causes of delayed hypersensitivity reactions, such as drug reacti...
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1
Acute myeloid leukemia (AML) is a hematopoietic malignancy. Chidamide has shown anti-cancer effect in different malignanci...
Utilization patterns of cardiovascular medications in patients with diabetes mellitus; a retrospective cross-sectional study, 2013-17
Utilization patterns of cardiovascular medications in patients with diabetes mellitus; a retrospective cross-sectional study, 2013-17
Diabetes Mellitus (DM) is a prominent health care issue worldwide. One of the most prevalent comorbidities of DM is cardio...
Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-finding trial
Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-finding trial
Colloid and/or co-load may be more effective than crystalloid for preventing postspinal anesthesia hypotension. We tested ...
Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer
Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer
Several studies have shown that the TGF-β signaling pathway plays a critical role in colorectal cancer (CRC) pathogen...
Identifying natural products for gastric cancer treatment through pharmacophore creation, 3D QSAR, virtual screening, and molecular dynamics studies
Identifying natural products for gastric cancer treatment through pharmacophore creation, 3D QSAR, virtual screening, and molecular dynamics studies
Gastric cancer (GC) is known as the fourth leading cause of cancer-related death and the fifth major cancer in the world, ...
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